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Carisoprodol carisoprodol taken with vicodin marketed under the brand name Soma among others, is a prescription drug marketed since 1959. It is a centrally acting skeletal muscle relaxant of the carbamate class and produces all the effects associated with barbiturates. Carisoprodol is a frequently prescribed muscle relaxant. In recent years, this drug has been increasingly abused. The effects of carisoprodol have been attributed to ... Carisoprodol is a frequently prescribed muscle relaxant. In recent years, this drug has been increasingly abused. The effects of carisoprodol have been attributed to its metabolite, meprobamate, a controlled substance that produces sedation via GABA A receptors (GABA A Rs). Carisoprodol-Mediated Modulation of GABA A Receptors: In Vitro and in Vivo Studies Lorie A. Gonzalez, Michael B. Gatch, Cynthia M. Taylor, Cathy L. Bell-Horner, The major metabolic pathway of carisoprodol involves its conversion to meprobamate. In the United States, carisoprodol is a Schedule IV controlled substance under the Controlled Substances Act of 1970. The diversion and abuse of the drug increased in the last decade. carisoprodol gaba - smoverlea.org We studied subunit-dependent actions of carisoprodol on GABA A receptors. • Direct gating and allosteric modulation effects are influenced by subunit isoforms.

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